Malaria

Nearly half the world’s population is at risk of malaria. With 229 million cases recorded in 2019 alone, progress towards disease eradication remains a challenge. The development of ‘fit-for-purpose’ diagnostic tests that identify different parasites, and can detect subclinical cases, drug resistance and mutations is vital if are to reach eradication. Designed to support such research and innovation, the FIND Specimen Bank holds 7,000 unique samples and 150,000 aliquots collected from patients in Africa, Latin America and Southeast Asia. Available to academic, non-profit, independent, and commercial researchers, FIND has the samples needed to break the chain of transmission and make new progress in disease control.

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Our collection

Sample types include whole blood, saliva, and urine from symptomatic/asymptomatic cases of varying parasite load. All collections take place at qualified clinics under a protocol approved by an Institutional Review Board, and with informed consent from patients.

A full list of sample types and characterization is provided below.

Sample types and categories

Specimen type	Characterization	Volume	Origin
Whole blood	*P. falciparum* from symptomatic & asymptomatic subjects (HRP2-positives & HRP2-negatives)	0.2 mL	Africa, Latin America, Southeast Asia
Whole blood	*P. vivax* from symptomatic & asymptomatic subjects	0.2 mL	Latin America, Southeast Asia
Whole blood	*P. malariae* from symptomatic & asymptomatic subjects	0.2 mL	Africa, Southeast Asia
Whole blood	*P. ovale* from asymptomatic subjects	0.2 mL	Africa, Latin America, Southeast Asia
Whole blood	*P. spp.*-negative from matching collection areas	0.2 mL	Africa, Latin America, Southeast Asia
Spiked whole blood	*P. knowlesi* culture isolates (A1.H1 line)	0.2 mL	Not applicable
Saliva	*P. falciparum* from symptomatic & asymptomatic subjects*	0.2 mL	Africa, Latin America
Saliva	*P. vivax* from symptomatic & asymptomatic subjects*	0.2 mL	Africa, Latin America
Saliva	*P. malariae* from symptomatic & asymptomatic subjects*	0.2 mL	Africa, Latin America, Southeast Asia
Saliva	*P. ovale* from symptomatic subjects*	0.2 mL	Africa
Saliva	*P. spp.–negative from matching collection areas	0.2 mL	Africa, Latin America
Urine	*P. falciparum* from symptomatic & asymptomatic subjects	1 mL	Africa, Latin America, Southeast Asia
Urine	*P. vivax* from symptomatic subjects	1 mL	Latin America
Urine	*P. malariae* from symptomatic & asymptomatic subjects*	1 mL	Africa, Southeast Asia
Urine	*P. spp.*–negative from matching collection areas	1 mL	Africa, Latin America, Southeast Asia

*Characterization is based on analysis of blood samples collected from the subjects.

Complete microbiological and clinical data are collected during enrolment and follow-up and are linked to biological specimens. Associated clinical and characterization data sets are also available upon request.

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More than a sample supplier

Target product profiles offer important guidance on the minimum and optimal performance/operational characteristics of priority diagnostic tests for malaria. For more information about this, the product development process, or for assistance identifying the number and type of samples needed, please contact our team at specimenbank@finddx.org.

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